Medical Issues
The analysis of vegetative status and motor-evacuation biliary tract function has been conducted in rescue workers of Russian Emercom and civilians with metabolic syndrome. The interaction between vegetative status rates and impaired bile-excreting regulation has been revealed. It was found out that sympathetic tone of vegetative nerve system domination is typical for rescue workers with metabolic syndrome. Unlike civilians, Russian Emercom rescue workers are characterized by impaired biliary tract motor function along with the development of biliary sludge and cholesterosis. At the same time, liver parenchymatous changes have been mostly observed in civil people.

Biological Issues
Clinical and laboratory markers of bone metabolism disorders were assessed in firefighters with varying degrees of dental changes in osteopenic syndrome associated with acid-related diseases. Studies have shown that the decrease of mineral density in osseous tissue is accompanied by changes in biochemical parameters: the level of parathyroid hormone and the concentration of total magnesium increase, the level of ionized calcium, total testosterone and free androgen index reduce. The interrelation of hormonal and metabolic parameters with diseases of hard tissues of teeth was shown. Acid-related diseases are accompanied by changes of mineral metabolism indicators. The lowest concentration of ionized calcium is observed in atrophic gastritis, the highest - in peptic ulcer.

The article is devoted to results of studies of the clinical features and laboratory manifestations of HIV infection, opportunistic infections, comorbidities and antiretroviral therapy among prisoners in Tajikistan. Prisoners comprise about 11 % of total number of HIV patients in the Republic. Importance of comprehensive laboratory diagnosis is stressed as a basis for prescribing all kinds of adequate treatment. The need to develop a medical and social support program for drug addicts and HIV-infected prisoners released from penitentiaries is discussed.

Social and Psychological Issues
Personality orientations were studied in 281 cadets and 78 specialists of the State Fire Service (SFS), EMERCOM of Russia. Based on severity of value preferences, examinees were divided into 3 groups according to the direction of life values: 1st - with a humanistic orientation, 2nd - with a pragmatic one, 3rd - equally oriented. The first group included 40 % of the students and 59 % of specialists, the 2nd - 47 and 33 %, and the 3rd - 13 and 8 %, respectively. Personality orientations in the individual cadets and SFS specialists significantly differed in terms of success in professional activity. Coincidence of such personal values as self-development, spiritual fulfillment, active social contacts and creativity, which characterize the humanistic orientation of the individual with the system of professional values, determines the formation of professional competence of employees of the SFS, EMERCOM of Russia. Severity of emotional dysfunctions was analyzed in SFS specialists with different professional experience and leading orientation of life values. Average indices of emotional disorders severity by V.V. Boyko questionnaire (73.3 ± 4.1) points for the entire sample give no grounds for diagnosing their emotional burnout. However, the results from a sample with work experience of 20 years shows that increased experience is associated with more frequent emotional disorders up to burnout, especially among workers with pragmatic value orientations.

The dynamics of mental status changes in personality traits and morbidity was assessed in 40 employees of law enforcement bodies (LEB) within 1 year after participation in the anti-terrorist operation in the Chechen Republic. Presence in a military conflict zone was established to significantly affect physical health and mental well-being of law enforcement officers; as a result, new premorbid personality features are acquired and existing features are modified. In 17.5 % of law enforcement officers negative border-line (non-pathological) consequences of participation in armed conflicts were revealed: signs of psychophysiological fatigue, mental stress, frequent and prolonged morbidity, increased pessimism, impulsivity, rigidity, aggression and nonconformism due to a lack of self-control. They may develop explosive or mixed reactivity, depression, neurotic or psychosomatic disorders, maladjustment. In 45 % of combatants, adaptive (compensating - protective) reactions dominated: suspiciousness, increased caution, sensitivity to danger, emotional coldness, the ability to think analytically based on intuition, minimum information and ignoring emotions; actualization of defense mechanisms of repression, projection and intellectual transformation of anxiety, subjective distancing from what is going on. 37.5 % of law enforcement officers demonstrate an active, rational and practical behavior, determination, courage, ability to unconventional problem solving, good intuition and quick response, wise attitude to life''s problems and optimism despite the traumatic situation.

Science of Science. Organization and Conduct of Research Studies
ISSN 2541-7487 (Online)