Correction with enterosorbents of adverse changes in the functional status of the sailors during prolonged voyage

Based on the analysis of the dynamics of physiological, psycho-physiological and biochemical parameters it was assessed the efficacy of enterosorbents as a means of correction the functional status of the sailors in the prolonged (54 days) voyage. The study was carried out with the participation of volunteers – crewmembers of a surface ship of the Navy of Russia (56 sailors, the average age of 19,3 ± 0,12 years). There were formed 3 equal groups in terms of age and professional military activities. In the group 1 (n = 19), the sailors received enterosorbent "Polisorb-MP", in the 2nd group (n = 18) – enterosorbent "Activated carbon". Group 3 (n = 19) was the control (placebo). The drugs were administrated orally in the last 20 days of sailing in a daily dose of 5 g once in the form of an aqueous suspension in 100–120 ml of water. It is shown that on the background of enterosorbents decreased functional stress the cardiovascular system and did not occurred the significant deterioration of sensorimotor coordination and sensorimotor reaction in sailors after voyage. It was observed less than in the control an increase in lactic acid, urea, malonic dialdehyde, medium mass molecules and circulating immune complexes levels in the blood. Positive influence of enterosorbents on the functional status of sailors is regarded as improving the flow of adaptation processes in the organism by reducing the metabolic (toxic) load on the organs of detoxification and excretion.

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