METABOLIC AND PATHOPHYSIOLOGICAL DISORDERS IN HUMAN ORGANISM DURING PROLONGED STARVATION
https://doi.org/10.25016/2541-7487-2018-0-2-109-116
Abstract
Relevance. The number of starving people throughout the world as well as global financial costs related to the development of alimentary-dependent conditions and diseases constantly increase. Intention. To review the scientific literature on the problems of metabolic and pathophysiological disorders caused by longterm starvation in human organism.
Methodology. The available domestic and foreign sources of scientific information were studied.
Results and Discussion. Paper describes the data on the pathogenesis of prolonged famine, on the endo- and exogenous causes of starvation, on qualitative and quantitative types of starvation, as well as the changes in metabolism of various organs and systems in completely starving organism during all periods of complete starvation (that of emergency, long-term adaptation, and decompensation) with their detailed endocrine-metabolic features. The results of the main research works by the Leningrad physicians who lived and worked in besieged Leningrad during the Great Patriotic War are recalled.
Conclusion. The information presented is important for biomedical science and health practice as well, since emergencies can be associated with prolonged starvation of people in the modern world.
About the Authors
L. P. Khoroshinina
Saint-Petersburg State Pediatric Medical University;
Saint Petersburg clinical hospital for veterans of wars
Russian Federation
Russian Federation
Lidiya Pavlovna Khoroshinina – Dr. Med. Sci. Prof.
Litovskaya Str., 2, St. Petersburg, 194100
Narodnaya Str., 21–2, St. Petersburg, 193079
L. P. Churilov
Saint-Petersburg University
Russian Federation
Russian Federation
Leonid Pavlovich Churilov – PhD Med. Sci. Associate Prof., Chairman of Pathology Dept
Universitetskaya Emb., 7/9, St. Petersburg, 199034
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Review
For citations:
Khoroshinina L.P., Churilov L.P. METABOLIC AND PATHOPHYSIOLOGICAL DISORDERS IN HUMAN ORGANISM DURING PROLONGED STARVATION. Medicо-Biological and Socio-Psychological Problems of Safety in Emergency Situations. 2018;(2):109-116. (In Russ.) https://doi.org/10.25016/2541-7487-2018-0-2-109-116
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