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Medicо-Biological and Socio-Psychological Problems of Safety in Emergency Situations

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Metabolic and hormonal disorders in women exposed to a high terrorism threat during puberty

https://doi.org/10.25016/2541-7487-2016-0-4-117-123

Abstract

Relevance. The psychological impact of high terrorist threat refers to the number of powerful stressors related to an immediate threat to life, which can lead to a wide range of neuro-emotional, physiological, and clinical changes that persist over years. Intention. To assess peculiarities of basic metabolism and hormonal regulation disorders in women exposed to a high terrorist threat during puberty. Methods. Case histories and medical records of 280 women of childbearing age from various districts of the Dagestan Republic (Russia) were analyzed. 162 women lived in areas exposed to the threat of terrorism and occupation by terrorists in September 1999. Parameters of the endocrine and immune systems as well as biochemical homeostasis were comparative described in women suffered psychological trauma associated with life threat vs women not suffered such traumas. Results and Discussion. Significant weight contributions to the structure of gynecological diseases in areas subjected to illegal occupation by terrorist forces It were revealed for dysmenorrhea, premenstrual syndrome and hyperprolactinemia syndrome. Metabolic disorders in women survivors of trauma in adolescence manifested as increased glucose level and decreased high density lipoproteins. Reproductive dysfunctions in women suffered psychological trauma due to a high terrorist threat are associated with increased concentrations of cortisol, prolactin and decreased concentrations of luteinizing hormone and estradiol. A key mechanism of the reproductive pathology is proved to be dysregulation of the endocrine system. Conclusion. For reproductive health, it is necessary to conduct psycho-corrective activities in women suffering psychological trauma associated with life threat.

About the Authors

Kepiya Temirkhanovna Temirkhanova
Institute of Experimental Medicine
Russian Federation


Sergey Georgievich Tsykunov
Institute of Experimental Medicine
Russian Federation


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Review

For citations:


Temirkhanova K.T., Tsykunov S.G. Metabolic and hormonal disorders in women exposed to a high terrorism threat during puberty. Medicо-Biological and Socio-Psychological Problems of Safety in Emergency Situations. 2016;(4):117-123. (In Russ.) https://doi.org/10.25016/2541-7487-2016-0-4-117-123

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