Calcification of the coronary arteries and lipid disorders in liquidators of the Chernobyl NPP disaster aftermath
https://doi.org/10.25016/2541-7487-2014-0-4-66-69
Abstract
Coronary artery calcinosis was assessed via multispiral computer tomography using Agatston score and blood lipid profiles were determined in persons engaged in elimination of the consequences of the Chernobyl accident. Study group included 65 men aged 52-78 years. In this group, calcification of coronary arteries was associated with increased levels of total cholesterol, cholesterol of low density lipoproteins, an atherogenic index, decreased level of high density lipoproteins. The interrelation was revealed between calcinosis score and total cholesterol, high density lipoproteins and calcinosis score.
About the Authors
T. V. Goreiko
The Nikiforov Russian Center of Emergency and Radiation Medicine, EMERCOM of Russia
Russian Federation
PhD Med. Sci. – Doctor, Department of Laboratory Clinical Diagnostics
Russian Federation
PhD Med. Sci. – Doctor, Department of Laboratory Clinical Diagnostics
L. B. Drygina
The Nikiforov Russian Center of Emergency and Radiation Medicine, EMERCOM of Russia
Russian Federation
Dr Biol. Sci. Prof., Head of the Laboratory
Russian Federation
Dr Biol. Sci. Prof., Head of the Laboratory
V. N. Khirmanov
The Nikiforov Russian Center of Emergency and Radiation Medicine, EMERCOM of Russia
Russian Federation
Dr Med. Sci. Prof., Head of Department of Cardiovascular Diseases
Russian Federation
Dr Med. Sci. Prof., Head of Department of Cardiovascular Diseases
References
1. Aronov D.M., Lupanov V.P. Ateroskleroz i koronarnaya bolezn' serdtsa [Atherosclerosis and ischemic hearty disease].Moskva. 2009. 248 p. (In Russ.)
2. Boeva O.I., Shcheglova E.V., Laipanova L.I. [et al.]. Analiz pokazatelei lipidnogo obmena pri kal'tsiniruyushchei bolezni aortal'nogo klapana [Analysis of lipid metabolism in aortic valve calcinosis].Fundamental'nye issledovaniya[Fundamentalresearch]. 2014. N 7, Part 1. P. 21–25. (In Russ.) кальцинирующей болезни аортального клапана // Фундаментальные исслед. – 2014. – No 7, ч. 1. – С. 21–25.
3. Connie W.T. [et al.]. Relations of Long-Term and Contemporary Lipid Levels and Lipid Genetic Risk Scores with Coronary Artery Calcium in the Framingham Heart Study // J. Am. Coll. Cardiol. – 2012 – Vol. 60, N 23. – P. 2364–2371.
4. Lazzini A., Lazzini S. Cardiovascular disease: an economical perspective // Curr. Pharm. Des. – 2009. – Vol. 15, N 10. – P. 1142–1156.
5. New S.E.P., Aikawa E. Molecular Imaging Insights into Early Inflammatory Stages of Arterial and Aortic Valve Calcification // Circulation Research. – 2011. – Vol. 108. – P. 1381–1391.
6. Schinke T., Karsenty G. Vascular calcification – a passive process in need of inhibitors // Nephrol. Dial. Transplant. – 2000. – Vol. 15, N 9. – P.1272–1274.
7. Towler D.A., Demer L.L. Thematic Series on the Pathobiology of Vascular Calcification An Introduction // Circ. Res. – 2011. – Vol. 108. – P. 1378–1380.
8. Wang Y. [et al.] Common genetic variants of MGP are associated with calcification on the arterial wall but not with calcification present in the atherosclerotic plaques // Circ. Cardiovasc. Genet. – 2013. – Vol. 6, N 3. – P. 271–278
9.
10.
Review
For citations:
Goreiko T.V., Drygina L.B., Khirmanov V.N. Calcification of the coronary arteries and lipid disorders in liquidators of the Chernobyl NPP disaster aftermath. Medicо-Biological and Socio-Psychological Problems of Safety in Emergency Situations. 2014;(4):66-69. (In Russ.) https://doi.org/10.25016/2541-7487-2014-0-4-66-69
Views:
274
Email this article 