Clinical and diagnostic value of cerebral white matter lesions in administrative profile specialists
https://doi.org/10.25016/2541-7487-2014-0-3-27-33
Abstract
There were examined 83 administrative professionals of EMERCOM of Russia at the age from 34 up to 65 years old. All participants underwent magnetic resonance imaging (MRI) to assess the presence and severity of cerebral white matter lesions. Gliosis foci (cerebral white matter lesions [WML]) were detected in 60 (72 %) participants. Association was established between WML and management experience, atherosclerosis markers, circadian blood pressure rhythm. The most significant factors of micro WML were increased carotid intima-media thickness, carotid atherosclerotic plaques and degree of stenosis. In patients without pathological changes in carotid walls, non-dipping blood pressure and morning blood pressure surge were the major risk factors. Micro WML were associated with severity of brain atrophy (substitution hydrocephalus).
About the Authors
V. N. Vasilev
The Nikiforov Russian Center of Emergency and Radiation Medicine, EMERCOM of Russia
Russian Federation
Neurologist, Department of Clinical Neurology
Russian Federation
Neurologist, Department of Clinical Neurology
V. V. Kindyashova
The Nikiforov Russian Center of Emergency and Radiation Medicine, EMERCOM of Russia
Russian Federation
Head of the Research Laboratory, Department of Clinical Neurology
Russian Federation
Head of the Research Laboratory, Department of Clinical Neurology
V. V. Kozhevnikov
The Nikiforov Russian Center of Emergency and Radiation Medicine, EMERCOM of Russia
Russian Federation
Researcher, Department of Clinical Neurology
Russian Federation
Researcher, Department of Clinical Neurology
O. V. Tikhomirova
The Nikiforov Russian Center of Emergency and Radiation Medicine, EMERCOM of Russia
Russian Federation
Dr. Med. Sci., Head of the Department of Clinical Neurology
Russian Federation
Dr. Med. Sci., Head of the Department of Clinical Neurology
I. P. Lomova
The Nikiforov Russian Center of Emergency and Radiation Medicine, EMERCOM of Russia
Russian Federation
PhD Med. Sci., Senior Researcher, Department of Clinical Neurology
Russian Federation
PhD Med. Sci., Senior Researcher, Department of Clinical Neurology
S. V. Serebryakova
The Nikiforov Russian Center of Emergency and Radiation Medicine, EMERCOM of Russia
Russian Federation
Dr. Med. Sci., Head of MRI consulting room, clinic No 1
Russian Federation
Dr. Med. Sci., Head of MRI consulting room, clinic No 1
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For citations:
Vasilev V.N., Kindyashova V.V., Kozhevnikov V.V., Tikhomirova O.V., Lomova I.P., Serebryakova S.V. Clinical and diagnostic value of cerebral white matter lesions in administrative profile specialists. Medicо-Biological and Socio-Psychological Problems of Safety in Emergency Situations. 2014;(3):27-33. (In Russ.) https://doi.org/10.25016/2541-7487-2014-0-3-27-33
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