НОВЫЕ ПОДХОДЫ В БИОЛОГИЧЕСКОЙ ДОЗИМЕТРИИ: СОЗДАНИЕ КОМПЛЕКСНЫХ БИОДОЗИМЕТРИЧЕСКИХ СИСТЕМ (ОБЗОР ЗАРУБЕЖНОЙ ЛИТЕРАТУРЫ)

Актуальность. В случае крупномасштабных радиационных инцидентов биологическая дозиметрия является важным инструментом, который может обеспечить своевременную оценку доз облучения, провести идентификацию лиц, подвергшихся облучению, для определения дальнейшего медицинского сопровождения.

Цель – оценка возможности использования нескольких биологических маркеров для создания комплексной биодозиметрической системы на основе данных литературы.

Методология. Поиск литературных источников проводился по базам данных MEDLINE, в поисковых системах PubMed, CyberLeninka, elibrary.ru с использованием терминов: радиация, облучение, биодозиметрия. В обзоре представлены результаты исследований из полнотекстовых источников литературы на английском языке.

Результаты и их анализ. Анализ литературных данных показал, что в зависимости от сценария инцидента для получения оценок доз с оптимальной скоростью и точностью можно применять комплекс различных биодозиметрических методов. Биологическая дозиметрия, используемая наряду с физической дозиметрией и клинической оценкой, позволяет определить степень воздействия ионизирующего излучения на отдельных пострадавших и лучшую терапевтическую стратегию. Комплексное применение нескольких биологических маркеров в биодозиметрической системе позволяет получать надежные оценки дозы облучения.

Заключение. Анализ данных, представленных в обзоре, показал, что совместное использование нескольких биологических маркеров и создание комплексной биодозиметрической системы позволит получить более точную оценку дозы облучения, что особенно актуально в случае радиационных аварий и инцидентов, когда данные физической дозиметрии отсутствуют.

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