Features of sexual development of girls whose mothers experienced a vital stress before pregnancy

Relevance. There are known negative effects of vital stress on reproductive function. Few studies assessed development of children whose mothers had been exposed to vital stress. Intention: To evaluate peculiarities of sexual development of girls whose mothers suffered vital stress due to the terrorist threat before pregnancy. Methods: Results of preventive medical examinations of 1590 girls in the Republic of Dagestan were analyzed; 800 of these girls were born to women exposed to the terrorist threat in 1999. Results and Discussion: The analysis showed that girls whose mothers experienced vital stress before pregnancy period had earlier and disturbed puberty manifested as earlier menarche and delayed establishment of regular menstrual cycle due to changes in humoral regulation. Conclusion. The obtained results show the long-term effects of mothers’ vital stress on puberty of their offspring.

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