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Dynamics of immunobiological indicators in recruits during adaptation to changing environmental conditions

https://doi.org/10.25016/2541-7487-2017-0-2-83-92

Abstract

Relevance. Moving to a distance with more than 3 hour time difference is a serious challenge for bodily functions. Intention. The purpose of research – to study consistent patterns of individual adaptogenesis based on immunobiological indices. Methods. Research data of 52 recruites during the first 6 months after their arrival to the place of service are given. A laboratory study of the exhaled air condensate (EAC), saliva, urine was carried out three times (3 days, 3rd and 6th month after moving to new climatogeographical and social conditions). The control group consisted of 108 healthy conscripts living permanently in the region. The groups were well balanced by age. For the study, substrates obtained by non-invasive sampling (condensation of exhaled air, saliva, urine) were used. The results obtained were processed using parametric analysis. Results and Discussion. It was revealed that all the changes in the parameters are subject to the same regularity – wavelike dynamics – a damped sinusoid, the amplitude and width of which depended on metabolism blocking or activating components to preserve homeostasis. Conclusion. As a result, there were proposed the markers of adaptation to changing environmental conditions in the first halfyear of service: total protein, uric acid and immunoglobulin A in the condensate of exhaled air; esterase and protein-carbohydrate ratio in the saliva; and nitrogen oxide and medium molecules in the urine. Their changes were statistically significant and fully reflected the course of adaptation reactions.

 

About the Authors

Eduard Viktorovich Luchaninov
Nikiforov Russian Center of Emergency and Radiation Medicine, EMERCOM of Russia
Russian Federation
Dr. Med. Sci, Head of the department


Marina Mikhailovna Tsvetkova
Pacific State Medical University MOH of Russia
Russian Federation
PhD Med. Sci., Associate Prof.


Valentina Nikolaevna Luchaninova
North-Western State Medical University named after I.I. Mechnikov
Russian Federation
Dr. Med. Sci. Prof.


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For citations:


Luchaninov E.V., Tsvetkova M.M., Luchaninova V.N. Dynamics of immunobiological indicators in recruits during adaptation to changing environmental conditions. Medicо-Biological and Socio-Psychological Problems of Safety in Emergency Situations. 2017;(2):83-92. (In Russ.) https://doi.org/10.25016/2541-7487-2017-0-2-83-92

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ISSN 1995-4441 (Print)
ISSN 2541-7487 (Online)