EFFECT OF HELICOBACTER PYLORI ON THE MORPHOLOGICAL STATUS OF THE GASTRIC MUCOSA IN CHRONIC GASTRITIS
https://doi.org/10.25016/2541-7487-2013-0-2-58-65
Abstract
The relationship was assessed between localiza tion of atrophy in 86 patients with chronic atrophic gastritis and different types of contamination of the mucous membrane of the stomach by Helicobacter pylori (H. pylori). The average age of the patients was (54.9 ± 1.6) years. Н. pylori was absent in 55.8 % of patients. In the presence of H. pylori infection, atrophic changes significantly more frequently (p < 0.05) are localized both in the mucosa of the body and antrum. In general, H. pylori does not affect disregeneration changes (intestinal metaplasia and dysplasia) in the antral mucosa of patients with chronic atrophic gastritis. However, colonic type intestinal metaplasia is detected significantly more frequently (p < 0.05) in the antral mucosa only at the persistence of H. pylori infection in the antrum lining than without it, which certainly increases the risk of stomach cancer.
About the Authors
I. M. Pavlovich
Militari Medical Academy named after S.M. Kirov, St. Petersburg
Russian Federation
Russian Federation
A. V. Gordienko
Militari Medical Academy named after S.M. Kirov, St. Petersburg
Russian Federation
Russian Federation
S. S. Batskov
The Nikiforov Russian Center of Emergency and Radiation Medicine, EMERCOM of Russia, St. Petersburg
Russian Federation
Russian Federation
D. V. Lavrenchuk
Militari Medical Academy named after S.M. Kirov, St. Petersburg
Russian Federation
Russian Federation
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Review
For citations:
Pavlovich I.M., Gordienko A.V., Batskov S.S., Lavrenchuk D.V. EFFECT OF HELICOBACTER PYLORI ON THE MORPHOLOGICAL STATUS OF THE GASTRIC MUCOSA IN CHRONIC GASTRITIS. Medicо-Biological and Socio-Psychological Problems of Safety in Emergency Situations. 2013;(2):32-35. (In Russ.) https://doi.org/10.25016/2541-7487-2013-0-2-58-65
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