Measuring the success of mental adaptation to extreme professional activities in the military with various alleles of genes regulating metabolism
https://doi.org/10.25016/2541-7487-2015-0-2-74-79
Abstract
Current mental state changes were assessed depending on the polymorphism of genes associated with metabolism in 570 male conscripts from units performing special tasks of power structures of the Republic of Belarus. The average age of servicemen was (21.3 ± 2.4) years. The correlation was detected between ACTN3, TFAM, PPARA and PPARGC1A alleles and mental adaptation to high physical loads of combat training missions during 7-day field exercise in accordance with the plan of troop training, tactical training guidance and field manuals. ACTN3 X, TFAM Thr, PPARA G and PPARGC1A Gly alleles were associated with high tolerance to physical stress. The features of the current mental state were established in servicemen based on their anxiety, well-being, activity and mood during combat training associated with high physical loads depending on the genotype of candidate genes. Screening of ACTN3, TFAM, PPARA PPARGC1A gene polymorphism helps to select subjects able to perform specific tasks associated with high physical activity.
About the Authors
A. O. Pyatibrat
The Nikiforov Russian Center of Emergency and Radiation Medicine, EMERCOM of Russia
Russian Federation
Russian Federation
PhD Med. Sci., Associate Prof., Head of the Research Department of the organization of scientific activity, Nikiforov Russian Center of Emergency and Radiation Medicine, EMERCOM of Russia (Russia, 194044, St. Petersburg, Academica Lebedeva Str., 4/2)
S. B. Melnov
International Sakharov Environmental University
Belarus
Belarus
Dr. Biol. Sci., Prof. of the Department of Environmental and Molecular Medicine International Sakharov Environmental University (Belarus, 220070, Minsk, Dolgobrodskaya Str., 23)
A. S. Kozlova
Republican Scientific and Practical Center of Sports
Belarus
Belarus
Master of Sci., Head of the Laboratory of Pharmacology and sports nutrition, Republican Scientific and Practical Center of Sports (Belarus,, 220007, Minsk, Voronianskogo, Str., 50/1)
E. G. Neronova
The Nikiforov Russian Center of Emergency and Radiation Medicine, EMERCOM of Russia
Russian Federation
Russian Federation
PhD Biol. Sci., Associate Prof., Head of Laboratory Nikiforov Russian Center of Emergency and Radiation Medicine, EMERCOM of Russia (Russia, 194044, St. Petersburg, Academica Lebedeva Str., 4/2)
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Review
For citations:
Pyatibrat A.O., Melnov S.B., Kozlova A.S., Neronova E.G. Measuring the success of mental adaptation to extreme professional activities in the military with various alleles of genes regulating metabolism. Medicо-Biological and Socio-Psychological Problems of Safety in Emergency Situations. 2015;(2):74-79. (In Russ.) https://doi.org/10.25016/2541-7487-2015-0-2-74-79
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