EFFECT OF ACUTE HYPOKINETIC STRESS ON LIVER FUNCTIONS
https://doi.org/10.25016/2541-7487-2013-0-4-61-65
Abstract
Abstract. An acute 4-hour hypokinetic stress was experimentally shown to induce qualitatively identical changes in the liver functional state and metabolic activity in rats with high or low resistance to hypoxia. This manifested in hypotension, bradycardia, decreased rectal temperature, respiration rate and oxygen intake as well as in disordered acid-alkaline balance with lactic acidosis signs. The rats demonstrated excretory, antitoxic and enzyme liver dysfunctions, with reduced energy potential. The degree of changes in the low-resistant rats was higher than in high-resistant animals.
About the Authors
I. V. Zarubina
Петербург Kirov Military Medical Academy, Saint-Petersburg
Russian Federation
Zarubina Irina Viktorovna - Doctor of biol. sci., Prof., senior scientist, Pharmacology Departmen
Russian Federation
Zarubina Irina Viktorovna - Doctor of biol. sci., Prof., senior scientist, Pharmacology Departmen
I. A. Yunusov
Петербург Kirov Military Medical Academy, Saint-Petersburg
Russian Federation
Yunusov Islomuddin Ayniddinovich - Ph, Pharmacology Department of Kirov Military medical Academy
Russian Federation
Yunusov Islomuddin Ayniddinovich - Ph, Pharmacology Department of Kirov Military medical Academy
P. D. Shabanov
Петербург Kirov Military Medical Academy, Saint-Petersburg
Russian Federation
Shabanov Petr Dmitrievich - MD, Prof., Head of Pharmacology Department
Russian Federation
Shabanov Petr Dmitrievich - MD, Prof., Head of Pharmacology Department
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Review
For citations:
Zarubina I.V., Yunusov I.A., Shabanov P.D. EFFECT OF ACUTE HYPOKINETIC STRESS ON LIVER FUNCTIONS. Medicо-Biological and Socio-Psychological Problems of Safety in Emergency Situations. 2013;(4):61-65. (In Russ.) https://doi.org/10.25016/2541-7487-2013-0-4-61-65
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