mchsrosМедико-биологические и социально-психологические проблемы безопасности в чрезвычайных ситуацияхMedicо-Biological and Socio-Psychological Problems of Safety in Emergency Situations1995-44412541-7487«The Nikiforov Russian Center of Emergency and Radiation Medicine»10.25016/2541-7487-2014-0-1-85-92mchsros-46Research ArticleБиологические проблемыBiological IssuesЗНАЧЕНИЕ БИОЭКОЛОГИЧЕСКОГО МОНИТОРИНГА СТОЙКИХ ОРГАНИЧЕСКИХ ЗАГРЯЗНИТЕЛЕЙ И ОЦЕНКА ИХ ГЕНОТОКСИЧЕСКИХ ЭФФЕКТОВ В СИСТЕМЕ ЭКОЛОГИЧЕСКОЙ БЕЗОПАСНОСТИValue bioecological monitoring and genotoxity of persistent organic pollutants for environmental safetyШахтамировИ. Я.ShakhtamirovI. Ya.

зав. каф., канд. сел.хоз. наук доц

PhD on Agric. Sci., Head of the Department

mutieva01@mail.ruКравцовВ. Ю.KravtsovV. Yu.

др биол. наук проф.

Dr. Biol. Sci., Prof.

kvyspb@rambler.ruЧеченский государственный университетРоссияChechen State UniversityRussian FederationВсероссийский центр экстренной и радиационной медицины им. А.М. Никифорова МЧС РоссииРоссияThe Nikiforov Russian Center of Emergrency and Radiation Medicine, EMERCOM of RussiaRussian Federation201418042016018592Copyright © Шахтамиров И.Я., Кравцов В.Ю., 20162016Шахтамиров И.Я., Кравцов В.Ю.Shakhtamirov I.Y., Kravtsov V.Y.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://mchsros.elpub.ru/jour/article/view/46

Канцерогенность стойких органических загрязнителей (СОЗ) в настоящее время доказана, однако, вместе с тем, их генотоксические эффекты, промотирующие канцерогенез, до сих пор не определены. Рыбы внутренних водоемов - выраженные гипераккумуляторы СОЗ (главным образом диоксинов). Специально проведенный аналитический обзор посвящен влиянию СОЗ на геномную нестабильность (генотоксические эффекты) у рыб. Проведенный в обзоре литературный анализ позволяет заключить, что у рыб, обитающих в водоемах, загрязненных СОЗ, практически всегда обнаруживается повышенная геномная нестабильность, оцененная микроядерным тестом. Таким образом, следует признать возможность генотоксических эффектов СОЗ в антропогенно-загрязненной внешней среде.

Currently, cancerogenic ability of persistent organic pollutants (POPs) has been proven, however their genotoxic effects promoting cancerogenesis has not been validated. Fish of inland waters are POPs hyperaccumulators (mainly dioxins). Effect of POPs on genomic instability (genotoxic effects) in fish was the topic of a specially conducted analytical review. Literature search allows for making conclusion that in fish living in POPs polluted waters, higher genomic instability revealed by micronucleus test has often been demonstrated. Thus, possibility of genotoxic effects of POPs in antropogenicly polluted environment should be admitted.

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The authors declare that there are no conflicts of interest present.